The test was positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). She consulted a doctor and gave her advice on bed rest and home quarantine from her family members after sending her for a real-time polymerase chain reaction (PCR) test of the nasopharyngeal swab. She complained of fever (38.5 ☌), dry cough, fatigue, and loss of smell and taste. The patient had a history of contact with her infected grandmother with COVID-19. We reported the first case of supraclavicular lymph node enlargement in a 12-year-old girl following COVID-19.Ī 12-year-old female presented with a neck mass in the right supraclavicular area of 1-month duration. However, there is no reported case of supraclavicular cervical lymphadenopathy due to COVID-19. reported three COVID-19 patients with cervical lymphadenopathy in level 2 (upper jugular group). Moreover, cervical lymphadenopathy following COVID-19 vaccines was reported. Many viruses, particularly in the pediatric population, may cause cervical lymphadenopathies like adenovirus, Epstein-Barr virus, herpes virus, coxsackievirus, and cytomegalovirus. There are various causes of neck masses these are broadly divided into three groups congenital or developmental, inflammatory (infectious or noninfectious), and tumors. The neck is the joining part between the head and body. There are various otorhinolaryngological manifestations as a result of the COVID-19 pandemic, including, but not limited to, smell and taste abnormalities, dysphonia, hearing loss, sore throat, nasal obstruction, and parotitis. It is essential to put COVID-19 in the differential diagnosis of cervical lymphadenopathy. To our best knowledge, this is the first case of supraclavicular lymphadenopathy in a child with COVID-19. The specimen was sent for histopathology and immunohistochemistry evaluation which confirmed the benign nature of the lymph node. Therefore, an excisional biopsy of the largest node was performed. Ultrasound and fine-needle aspiration cytology were suspicious. Physical examination revealed painless, multiple, and mobile supraclavicular lymph nodes. Seven days later, she complained of supraclavicular swelling. The symptoms were resolved within 10 days. Case presentationĪ 12-year-old girl presented with fever, cough, fatigue, anosmia, and ageusia. However, there is no yet reporting a case of supraclavicular cervical lymphadenopathy due to COVID-19. Many cases of cervical lymphadenopathy after the COVID-19 vaccine were reported. The sensitivity and specificity of fine-needle aspiration biopsy in detecting a malignancy range from 77% to 97% and 93% to 100%, respectively.Cervical lymphadenopathy in children is a common problem in daily clinical practice. If imaging rules out involvement of underlying vital structures, a fine-needle aspiration biopsy can be performed, providing diagnostic information via cytology, Gram stain, and bacterial and acid-fast bacilli cultures. Computed tomography angiography is recommended over magnetic resonance angiography for the evaluation of pulsatile neck masses. Contrast-enhanced computed tomography is the initial diagnostic test of choice in adults. If the history and physical examination do not find an obvious cause, imaging and surgical tools are helpful. Etiologies can be grouped according to whether the onset/duration is acute (e.g., infectious), subacute (e.g., squamous cell carcinoma), or chronic (e.g., thyroid), and further narrowed by patient demographics. The first goal is to determine if the mass is malignant or benign malignancies are more common in adult smokers older than 40 years. Neck masses are often seen in clinical practice, and the family physician should be able to determine the etiology of a mass using organized, efficient diagnostic methods.
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